Peptideshop online The term "peptide 257" often leads researchers and scientists to a specific and highly studied molecule: the OVA Peptide (257-264). This peptide is a crucial component in immunological research, particularly in understanding T-cell responses and vaccine development. Its significance lies in its role as a class I (Kb)-restricted peptide epitope of OVA, a fragment derived from ovalbumin, the major protein found in egg whites. This article will delve into the intricacies of peptide 257, exploring its structure, function, and applications, drawing upon information from scientific literature and commercial suppliers.
At its core, peptide 257 refers to a specific sequence of amino acids within the ovalbumin protein.OVA Peptide (257-264)(CAS号1262751-08-5),肽序列Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu,是鸡卵清蛋白(OVA)的核心抗原表位,兼具抗原特异性免疫激活与免疫耐受调控双重活性, ... This particular segment, spanning from amino acid 257 to 264, is known by its sequence SIINFEKL. It is an octameric peptide, meaning it is composed of eight amino acids linked together by peptide bonds. The precise sequence and its presentation by the immune system make it a valuable tool for studying immune responses.
The primary function and significance of OVA Peptide (257-264) stem from its interaction with the immune system's major histocompatibility complex (MHC) molecules.Ova peptide (257-264) | C45H74N10O13 - PubChem - NIH Specifically, it is recognized as a class I (Kb)-restricted peptide epitope. This means that it is presented by the Class I MHC molecule, H-2Kb, on the surface of cells. This presentation is a critical step in the adaptive immune response, signaling to cytotoxic T lymphocytes (CTLs), also known as CD8+ T cells, that the cell is either infected or abnormal. The stimulation of these CD8+ cells and their cytotoxic T lymphocyte response is a key area of investigation when using this peptide.
The OVA Peptide (257-264) is widely used in experimental immunology as a model antigen.OVA-G4 Peptide, SIIGFEKL, OVA (257-264) Variant - 1 mg Its well-defined nature and immunogenicity make it ideal for a variety of research purposes.Ovalbumin(257-264) antigen peptide (E-PP-1667) For instance, it is frequently employed to test new adjuvant in immunotherapeutic vaccine development.Ovalbumin-derived peptideknown to arise from a natural processing of ovalbumin H-2b mouse cells. Subcutaneous immunization with this peptide could induce OVA- ... Adjuvants are substances added to vaccines to enhance the immune response, and the OVA 257-264 model allows researchers to rigorously assess the efficacy of new adjuvant formulationsThis is aclass I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.. Furthermore, its ability to stimulate a robust immune response has led to its investigation in the context of immunotherapeutic vaccine developmentHBV controlPeptidePool (>95% HPLC). Thispeptidepool consists of 9peptides, each corresponding to a defined HLA class I-restricted T cell epitope from Hepatitis B virus (HBV). €215.00*. Add to shopping cart. HCMVA (IE1)PeptidePool.Peptidepool of 120 overlappingpeptidesderived from apeptide....
The availability of peptide 257 is widespread through various scientific suppliers. Companies offer Research-grade Ova 257 264 Peptide for laboratory use, often specifying purity levels and forms such as OVA Peptide(257-264) TFAOVA 257-264 (SIINFEKL) is a well-characterized, immunodominant epitope derived from chicken ovalbumin protein (Uniprot P01012).. The "TFA" in the name refers to trifluoroacetic acid, a common counterion used during peptide synthesis and purification, ensuring stability and purity. These suppliers provide detailed information, including CAS numbers (e.g.OVA Peptide 257-264 2TFA. 别名: (2S,5S,8S,11S,14S,17S,20S,23S)-23-amino-14-(2-amino-2-oxoethyl)-5-(4-aminobutyl)-11-benzyl-17,20-di((S)-sec-butyl)-8-(2 ..., CAS NOOVA 257-264 scrambled (FILKSINE). 1262751-08-5), chemical structures, and molecular formulas (e.g., C45H74N10O13 as listed for Ova peptide (257-264) on PubChem).
Beyond its direct use in immune stimulation, the OVA Peptide (257-264) is also studied for its structural properties. It can form a stable hydrogel, and its linear structure, formed by the linkage of eight amino acids via peptide bonds, contributes to its specific binding to MHC molecules. The precise spatial arrangement of the amino acids in the OVA [257-264] Peptide allows for specific binding to the H-2Kb molecule, a characteristic that can be further probed using specific antibodies like the 25-D1.16 monoclonal antibody, which reacts with the ovalbumin-derived peptide SIINFEKL bound to H-2Kb.
While the primary focus of peptide 257 is in immunological research, the broader concept of peptides extends into other fields, such as skincare. However, the context of "peptide 257" overwhelmingly points towards its immunological roleThis is aclass I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.. When searching for related terms, one might encounter peptide catalogs, peptide shops online, and discussions about cell peptides or bulk peptides online.OVA Peptide(257-264) 是OVA 的I 类(Kb)-限制性肽表位,其中OVA 是一种来自卵清蛋白的八聚体肽,由I 类MHC 分子H-2Kb 所呈递。 These broader searches highlight the diverse applications and commercial availability of peptides in general, but the specific query for "peptide 257" narrows the focus to the OVA (257-264) epitopeOVA Peptide(257-264) TFA是OVA 的I 类(Kb)-限制性肽表位,它是一种八聚体肽,可以来自I 类MHC 分子H-2Kb 所呈现的卵清蛋白。 MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务. Custom Peptide Synthesis. OVA Peptide(257-264) TFA. OVA Peptide(257-264) TFA Chemical Structure. CAS No. : 1262751-08-5..
In summary, peptide 257, specifically the OVA Peptide (257-264), is a well-characterized and indispensable tool in immunologyOVA Peptide(257-264) TFA - 美国APExBIO中文官网. Its role as a class I (Kb)-restricted peptide epitope of OVA, presented by the H-2Kb molecule, makes it crucial for studying T-cell mediated immunity, vaccine development, and understanding antigen presentationInvivoGen provides two peptides from the ovalbumin (OVA) model antigen:OVA 257-264 is a class I (Kb)-restricted peptide epitopeof the ovalbumin protein .... The availability of OVA Peptide 257-264 2TFA and other forms from various suppliers underscores its importance in scientific research.Buy Ova 257 264 Peptide for Sale Online While the term "peptide" has broader applications, "peptide 257" is unequivocally linked to this specific, immunologically significant fragment of ovalbumin.
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